Varaico: Literature-Extracted Genetic Variants

PTGS2

723 papers

RefSeq Summary

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of...

Pfam Domains

An_peroxidaseaa 204–562UCSCAnimal haem peroxidase

Gene Aliases

HGNC Name

prostaglandin-endoperoxide synthase 2

HGNC Previous Name

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000963.4

p.H374D

c.1120C>G

Surrounding Variants

1 paper

NM_000963.4

p.Y371F

c.1112A>T

1 paper

NM_000963.4

p.Y371_H372insGAT

c.1111_1115ins9

1 paper

NM_000963.4

p.F367F

c.1101T>C

1 paper

NM_000963.4

p.F381V

c.1141T>G

1 paper

NM_000963.4

p.F381L

c.1141T>C

1 paper

NM_000963.4

p.F381S

c.1142T>C

1 paper

NM_000963.4

p.F381L

c.1143T>G

1 paper

NM_000963.4

p.F381L

c.1143T>A

3 papers

NM_000963.4

p.Q382*

c.1144C>T

1 paper

NM_000963.4

p.A364P

c.1090G>C

1 paper

NM_000963.4

p.H384R

c.1151A>G

1 paper

NM_000963.4

p.I363N

c.1088T>A