Varaico: Literature-Extracted Genetic Variants

PTGS2

723 papers

RefSeq Summary

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of...

Pfam Domains

An_peroxidaseaa 204–562UCSCAnimal haem peroxidase

Gene Aliases

HGNC Name

prostaglandin-endoperoxide synthase 2

HGNC Previous Name

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000963.4

p.W309*

c.927G>A

Surrounding Variants

7 papers

NM_000963.4

p.W309S

c.926G>C

1 paper

NM_000963.4

p.G310R

c.928G>C

1 paper

NM_000963.4

p.W309*

c.926G>A

1 paper

NM_000963.4

p.G310V

c.929G>T

1 paper

NM_000963.4

p.G310D

c.929G>A

2 papers

NM_000963.4

p.E308G

c.923A>G

1 paper

NM_000963.4

p.E305*

c.913G>T

1 paper

NM_000963.4

p.E305K

c.913G>A

1 paper

NM_000963.4

p.Q316R

c.947A>G

1 paper

NM_000963.4

p.T317I

c.950C>T

1 paper

NM_000963.4

p.D300H

c.898G>C

1 paper

NM_000963.4

p.C299C

c.897C>T