Varaico: Literature-Extracted Genetic Variants

PTGS2

723 papers

RefSeq Summary

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of...

Pfam Domains

An_peroxidaseaa 204–562UCSCAnimal haem peroxidase

Gene Aliases

HGNC Name

prostaglandin-endoperoxide synthase 2

HGNC Previous Name

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000963.4

p.I290T

c.869T>C

Surrounding Variants

1 paper

NM_000963.4

p.W291G

c.871T>G

1 paper

NM_000963.4

p.W291R

c.871T>C

1 paper

NM_000963.4

p.W291R

c.871T>A

1 paper

NM_000963.4

p.W291*

c.873G>A

3 papers

NM_000963.4

p.A288D

c.863C>A

2 papers

NM_000963.4

p.R293Q

c.878G>A

1 paper

NM_000963.4

p.Y287H

c.859T>C

1 paper

NM_000963.4

p.E294*

c.880G>T

1 paper

NM_000963.4

p.E294Q

c.880G>C

1 paper

NM_000963.4

p.M286T

c.857T>C

1 paper

NM_000963.4

p.M286V

c.856A>G

2 papers

NM_000963.4

p.H295R

c.884A>G