Varaico: Literature-Extracted Genetic Variants

PTGS2

723 papers

RefSeq Summary

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of...

Pfam Domains

An_peroxidaseaa 204–562UCSCAnimal haem peroxidase

Gene Aliases

HGNC Name

prostaglandin-endoperoxide synthase 2

HGNC Previous Name

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000963.4

p.F278S

c.833T>C

Surrounding Variants

1 paper

NM_000963.4

p.V277insFs

c.830_831insT

1 paper

NM_000963.4

p.V277delFs

c.830delA

13 papers

NM_000963.4

p.G279G

c.837T>C

1 paper

NM_000963.4

p.L280L

c.838C>T

1 paper

NM_000963.4

p.G283S

c.847G>A

1 paper

NM_000963.4

p.G283D

c.848G>A

1 paper

NM_000963.4

p.M286V

c.856A>G

1 paper

NM_000963.4

p.M286T

c.857T>C

1 paper

NM_000963.4

p.R270P

c.809G>C

2 papers

NM_000963.4

p.R270W

c.808C>T

1 paper

NM_000963.4

p.Y287H

c.859T>C

1 paper

NM_000963.4

p.H268Q

c.804T>G