Varaico: Literature-Extracted Genetic Variants

PTGS2

723 papers

RefSeq Summary

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of...

Pfam Domains

An_peroxidaseaa 204–562UCSCAnimal haem peroxidase

Gene Aliases

HGNC Name

prostaglandin-endoperoxide synthase 2

HGNC Previous Name

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000963.4

p.H268Q

c.804T>A

Surrounding Variants

1 paper

NM_000963.4

p.H268Q

c.804T>G

1 paper

NM_000963.4

p.H268Y

c.802C>T

2 papers

NM_000963.4

p.R270W

c.808C>T

1 paper

NM_000963.4

p.R270P

c.809G>C

1 paper

NM_000963.4

p.P266L

c.797C>T

1 paper

NM_000963.4

p.V265V

c.795C>T

1 paper

NM_000963.4

p.P263L

c.788C>T

1 paper

NM_000963.4

p.P262P

c.786T>C

1 paper

NM_000963.4

p.P262L

c.785C>T

1 paper

NM_000963.4

p.Y261C

c.782A>G

1 paper

NM_000963.4

p.V277insFs

c.830_831insT

1 paper

NM_000963.4

p.V277delFs

c.830delA