Varaico: Literature-Extracted Genetic Variants

PTGS2

723 papers

RefSeq Summary

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of...

Pfam Domains

An_peroxidaseaa 204–562UCSCAnimal haem peroxidase

Gene Aliases

HGNC Name

prostaglandin-endoperoxide synthase 2

HGNC Previous Name

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000963.4

p.H218Y

c.652C>T

Surrounding Variants

1 paper

NM_000963.4

p.I219N

c.656T>A

1 paper

NM_000963.4

p.D215D

c.645C>T

2 papers

NM_000963.4

p.Y220C

c.659A>G

1 paper

NM_000963.4

p.G221S

c.661G>A

1 paper

NM_000963.4

p.D215N

c.643G>A

1 paper

NM_000963.4

p.E222K

c.664G>A

1 paper

NM_000963.4

p.G213_V214Splc

c.640-1G>T

1 paper

NM_000963.4

p.E222G

c.665A>G

1 paper

NM_000963.4

p.L224M

c.670C>A

1 paper

NM_000963.4

p.R226S

c.678A>T

1 paper

NM_000963.4

p.R226S

c.678A>C

1 paper

NM_000963.4

p.Q227P

c.680A>C