Varaico: Literature-Extracted Genetic Variants

PTGS2

723 papers

RefSeq Summary

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of...

Pfam Domains

An_peroxidaseaa 204–562UCSCAnimal haem peroxidase

Gene Aliases

HGNC Name

prostaglandin-endoperoxide synthase 2

HGNC Previous Name

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_000963.4

p.Q39K

c.115C>A

Surrounding Variants

1 paper

NM_000963.4

p.Q39E

c.115C>G

1 paper

NM_000963.4

p.D38V

c.113A>T

1 paper

NM_000963.4

p.F37F

c.111T>C

1 paper

NM_000963.4

p.K41E

c.121A>G

1 paper

NM_000963.4

p.G36E

c.107G>A

1 paper

NM_000963.4

p.C42G

c.124T>G

1 paper

NM_000963.4

p.C42F

c.125G>T

1 paper

NM_000963.4

p.V35A

c.104T>C

1 paper

NM_000963.4

p.D43_C44insFs

c.129_130insC

1 paper

NM_000963.4

p.S34I

c.101G>T

2 papers

NM_000963.4

p.M33R

c.98T>G

1 paper

NM_000963.4

p.M33T

c.98T>C