Varaico: Literature-Extracted Genetic Variants

PTGS2

723 papers

RefSeq Summary

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of...

Pfam Domains

An_peroxidaseaa 204–562UCSCAnimal haem peroxidase

Gene Aliases

HGNC Name

prostaglandin-endoperoxide synthase 2

HGNC Previous Name

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_000963.4

p.T17I

c.50C>T

Surrounding Variants

1 paper

NM_000963.4

p.T17A

c.49A>G

2 papers

NM_000963.4

p.L14H

c.41T>A

1 paper

NM_000963.4

p.L12V

c.34C>G

1 paper

NM_000963.4

p.A10A

c.30G>T

1 paper

NM_000963.4

p.A10V

c.29C>T

4 papers

NM_000963.4

p.L8L

c.22C>T

1 paper

NM_000963.4

p.L7P

c.20T>C

1 paper

NM_000963.4

p.L6Q

c.17T>A

1 paper

NM_000963.4

p.A5G

c.14C>G

1 paper

NM_000963.4

p.A5S

c.13G>T

1 paper

NM_000963.4

p.A5P

c.13G>C

1 paper

NM_000963.4

p.A5T

c.13G>A