Varaico: Literature-Extracted Genetic Variants

PTK6

95 papers

RefSeq Summary

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epit...

Pfam Domains

SH3_1aa 14–64UCSCSH3 domain

SH2aa 78–155UCSCSH2 domain

PK_Tyr_Ser-Thraa 191–441UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

protein tyrosine kinase 6

HGNC Previous Name

PTK6 protein tyrosine kinase 6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005975.4

p.Y342*

c.1026C>G

Surrounding Variants

1 paper

NM_005975.4

p.Y342*

c.1026C>A

1 paper

NM_005975.4

p.L343F

c.1027C>T

1 paper

NM_005975.4

p.N348N

c.1044T>C

1 paper

NM_005975.4

p.K352R

c.1055A>G

1 paper

NM_005975.4

p.P356T

c.1066C>A

1 paper

NM_005975.4

p.S365F

c.1094C>T

1 paper

NM_005975.4

p.T366A

c.1096A>G

1 paper

NM_005975.4

p.H378Q

c.1134T>G

1 paper

NM_005975.4

p.H378Q

c.1134T>A

1 paper

NM_005975.4

p.E379Q

c.1135G>C

1 paper

NM_005975.4

p.E379E

c.1137G>A

1 paper

NM_005975.4

p.M380V

c.1138A>G