Varaico: Literature-Extracted Genetic Variants

PTK6

95 papers

RefSeq Summary

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epit...

Pfam Domains

SH3_1aa 14–64UCSCSH3 domain

SH2aa 78–155UCSCSH2 domain

PK_Tyr_Ser-Thraa 191–441UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

protein tyrosine kinase 6

HGNC Previous Name

PTK6 protein tyrosine kinase 6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_005975.4

p.P179A

c.535C>G

Surrounding Variants

2 papers

NM_005975.4

p.P177A

c.529C>G

1 paper

NM_005975.4

p.W181*

c.542G>A

1 paper

NM_005975.4

p.W181*

c.543G>A

2 papers

NM_005975.4

p.P175A

c.523C>G

2 papers

NM_005975.4

p.P187A

c.559C>G

1 paper

NM_005975.4

p.P187P

c.561G>A

1 paper

NM_005975.4

p.T192M

c.575C>T

1 paper

NM_005975.4

p.F202S

c.605T>C

2 papers

NM_005975.4

p.W210*

c.629G>A

1 paper

NM_005975.4

p.W210C

c.630G>T

1 paper

NM_005975.4

p.W210C

c.630G>C

2 papers

NM_005975.4

p.W210*

c.630G>A