Varaico: Literature-Extracted Genetic Variants

PTK6

95 papers

RefSeq Summary

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epit...

Pfam Domains

SH3_1aa 14–64UCSCSH3 domain

SH2aa 78–155UCSCSH2 domain

PK_Tyr_Ser-Thraa 191–441UCSCProtein tyrosine and serine/threonine kinase

Gene Aliases

HGNC Name

protein tyrosine kinase 6

HGNC Previous Name

PTK6 protein tyrosine kinase 6

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_005975.4

p.T23K

c.68C>A

Surrounding Variants

1 paper

NM_005975.4

p.D24H

c.70G>C

1 paper

NM_005975.4

p.R22W

c.64C>T

2 papers

NM_005975.4

p.L16F

c.46C>T

1 paper

NM_005975.4

p.A31E

c.92C>A

1 paper

NM_005975.4

p.G10G

c.30C>A

1 paper

NM_005975.4

p.G10V

c.29G>T

1 paper

NM_005975.4

p.H8D

c.22C>G

1 paper

NM_005975.4

p.R4R

c.12G>C

1 paper

NM_005975.4

p.W44L

c.131G>T

1 paper

NM_005975.4

p.W44*

c.131G>A

1 paper

NM_005975.4

p.W44*

c.132G>A

1 paper

NM_005975.4

p.W46*

c.137G>A