Varaico: Literature-Extracted Genetic Variants

PTN

58 papers

RefSeq Summary

The protein encoded by this gene is a secreted heparin-binding growth factor. The protein has significant roles in cell growth and survival, cell migration, angiogenesis and tumorigenesis. Alternative...

Pfam Domains

PTN_MK_Naa 34–95UCSCPTN/MK heparin-binding protein family, N-terminal domain

PTN_MK_Caa 96–161UCSCPTN/MK heparin-binding protein family, C-terminal domain

Gene Aliases

HGNC Name

pleiotrophin

HGNC Previous Symbol

NEGF1

Papers

RefSeq ID

Protein change

DNA change

1–12 of 43 variants

2 papers

NM_002825.7

p.R71Q

c.212G>A

2 papers

NM_002825.7

p.E98Q

c.292G>C

1 paper

NM_002825.7

p.M1L

c.1A>T

1 paper

NM_002825.7

p.M1L

c.1A>C

1 paper

NM_002825.7

p.R10L

c.29G>T

1 paper

NM_002825.7

p.T29I

c.86C>T

1 paper

NM_002825.7

p.A30P

c.88G>C

1 paper

NM_002825.7

p.V42insFs

c.124_125insA

1 paper

NM_002825.7

p.K41delFs

c.123delT

1 paper

NM_002825.7

p.V42fs

c.124_125fs

1 paper

NM_002825.7

p.S53fs

c.157_158fs

1 paper

NM_002825.7

p.V54L

c.160G>T