Varaico: Literature-Extracted Genetic Variants

PTN

58 papers

RefSeq Summary

The protein encoded by this gene is a secreted heparin-binding growth factor. The protein has significant roles in cell growth and survival, cell migration, angiogenesis and tumorigenesis. Alternative...

Pfam Domains

PTN_MK_Naa 34–95UCSCPTN/MK heparin-binding protein family, N-terminal domain

PTN_MK_Caa 96–161UCSCPTN/MK heparin-binding protein family, C-terminal domain

Gene Aliases

HGNC Name

pleiotrophin

HGNC Previous Symbol

NEGF1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002825.7

p.E98Q

c.292G>C

Surrounding Variants

1 paper

NM_002825.7

p.A97V

c.290C>T

1 paper

NM_002825.7

p.F103S

c.308T>C

1 paper

NM_002825.7

p.A105D

c.314C>A

1 paper

NM_002825.7

p.D110H

c.328G>C

1 paper

NM_002825.7

p.S121G

c.361A>G

1 paper

NM_002825.7

p.R124_A125insA

c.370_374ins3

1 paper

NM_002825.7

p.A125V

c.374C>T

1 paper

NM_002825.7

p.N128H

c.382A>C

1 paper

NM_002825.7

p.E130K

c.388G>A

1 paper

NM_002825.7

p.K146E

c.436A>G

1 paper

NM_002825.7

p.K146Q

c.436A>C

1 paper

NM_002825.7

p.A151S

c.451G>T