Varaico: Literature-Extracted Genetic Variants

PTN

58 papers

RefSeq Summary

The protein encoded by this gene is a secreted heparin-binding growth factor. The protein has significant roles in cell growth and survival, cell migration, angiogenesis and tumorigenesis. Alternative...

Pfam Domains

PTN_MK_Naa 34–95UCSCPTN/MK heparin-binding protein family, N-terminal domain

PTN_MK_Caa 96–161UCSCPTN/MK heparin-binding protein family, C-terminal domain

Gene Aliases

HGNC Name

pleiotrophin

HGNC Previous Symbol

NEGF1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002825.7

p.K41delFs

c.123delT

Surrounding Variants

1 paper

NM_002825.7

p.V42insFs

c.124_125insA

1 paper

NM_002825.7

p.V42fs

c.124_125fs

1 paper

NM_002825.7

p.S53fs

c.157_158fs

1 paper

NM_002825.7

p.V54L

c.160G>T

1 paper

NM_002825.7

p.V54L

c.160G>C

1 paper

NM_002825.7

p.C55F

c.164G>T

1 paper

NM_002825.7

p.T58S

c.172A>T

1 paper

NM_002825.7

p.T58S

c.173C>G

1 paper

NM_002825.7

p.G60E

c.179G>A

1 paper

NM_002825.7

p.G63W

c.187G>T

1 paper

NM_002825.7

p.R67Q

c.200G>A

1 paper

NM_002825.7

p.E68D

c.204G>T