Varaico: Literature-Extracted Genetic Variants

PTPN11

3,412 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

SH2aa 6–81UCSCSH2 domain

SH2aa 112–197UCSCSH2 domain

Y_phosphataseaa 273–520UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 11

HGNC Previous Symbol

NS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_002834.5

p.H8Y

c.22C>T

Surrounding Variants

1 paper

NM_002834.5

p.H8N

c.22C>A

1 paper

NM_002834.5

p.H8insFs

c.23dupA

1 paper

NM_002834.5

p.H8Q

c.24C>A

1 paper

NM_002834.5

p.H8Q

c.24C>G

1 paper

NM_002834.5

p.F7Y

c.20T>A

1 paper

NM_002834.5

p.P9T

c.25C>A

1 paper

NM_002834.5

p.F7V

c.19T>G

1 paper

NM_002834.5

p.P9Q

c.26C>A

1 paper

NM_002834.5

p.P9R

c.26C>G

1 paper

NM_002834.5

p.W6*

c.18G>A

1 paper

NM_002834.5

p.W6*

c.17G>A

1 paper

NM_002834.5

p.W6L

c.17G>T