Varaico: Literature-Extracted Genetic Variants

PTPN11

3,412 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

SH2aa 6–81UCSCSH2 domain

SH2aa 112–197UCSCSH2 domain

Y_phosphataseaa 273–520UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 11

HGNC Previous Symbol

NS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002834.5

p.A16S

c.46G>T

Surrounding Variants

3 papers

NM_002834.5

p.A16T

c.46G>A

1 paper

NM_002834.5

p.A16P

c.46G>C

1 paper

NM_002834.5

p.A16E

c.47C>A

2 papers

NM_002834.5

p.A16G

c.47C>G

2 papers

NM_002834.5

p.A16V

c.47C>T

1 paper

NM_002834.5

p.E15D

c.45G>C

1 paper

NM_002834.5

p.E15D

c.45G>T

1 paper

NM_002834.5

p.E15A

c.44A>C

2 papers

NM_002834.5

p.A16A

c.48A>G

1 paper

NM_002834.5

p.E15G

c.44A>G

2 papers

NM_002834.5

p.E15V

c.44A>T

3 papers

NM_002834.5

p.E17K

c.49G>A