Varaico: Literature-Extracted Genetic Variants

PTPN11

3,412 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

SH2aa 6–81UCSCSH2 domain

SH2aa 112–197UCSCSH2 domain

Y_phosphataseaa 273–520UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 11

HGNC Previous Symbol

NS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002834.5

p.G27A

c.80G>C

Surrounding Variants

3 papers

NM_002834.5

p.G27D

c.80G>A

1 paper

NM_002834.5

p.G27V

c.80G>T

2 papers

NM_002834.5

p.G27S

c.79G>A

1 paper

NM_002834.5

p.G27R

c.79G>C

1 paper

NM_002834.5

p.G27C

c.79G>T

3 papers

NM_002834.5

p.S28R

c.82A>C

1 paper

NM_002834.5

p.S28G

c.82A>G

1 paper

NM_002834.5

p.S28C

c.82A>T

1 paper

NM_002834.5

p.D26E

c.78T>A

1 paper

NM_002834.5

p.D26E

c.78T>G

3 papers

NM_002834.5

p.D26A

c.77A>C

2 papers

NM_002834.5

p.D26G

c.77A>G