Varaico: Literature-Extracted Genetic Variants

PTPN11

3,412 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

SH2aa 6–81UCSCSH2 domain

SH2aa 112–197UCSCSH2 domain

Y_phosphataseaa 273–520UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 11

HGNC Previous Symbol

NS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002834.5

p.S36G

c.106A>G

Surrounding Variants

1 paper

NM_002834.5

p.S36R

c.106A>C

2 papers

NM_002834.5

p.S36C

c.106A>T

1 paper

NM_002834.5

p.K35N

c.105A>C

1 paper

NM_002834.5

p.K35K

c.105A>G

1 paper

NM_002834.5

p.K35N

c.105A>T

1 paper

NM_002834.5

p.S36N

c.107G>A

1 paper

NM_002834.5

p.S36T

c.107G>C

1 paper

NM_002834.5

p.S36I

c.107G>T

1 paper

NM_002834.5

p.K35T

c.104A>C

1 paper

NM_002834.5

p.K35R

c.104A>G

1 paper

NM_002834.5

p.K35I

c.104A>T

1 paper

NM_002834.5

p.S36R

c.108T>A