Varaico: Literature-Extracted Genetic Variants

PTPN11

3,412 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

SH2aa 6–81UCSCSH2 domain

SH2aa 112–197UCSCSH2 domain

Y_phosphataseaa 273–520UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 11

HGNC Previous Symbol

NS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002834.5

p.S36R

c.108T>A

Surrounding Variants

1 paper

NM_002834.5

p.S36R

c.108T>G

1 paper

NM_002834.5

p.N37insFs

c.110dupA

1 paper

NM_002834.5

p.N37H

c.109A>C

1 paper

NM_002834.5

p.N37D

c.109A>G

1 paper

NM_002834.5

p.N37Y

c.109A>T

1 paper

NM_002834.5

p.S36N

c.107G>A

1 paper

NM_002834.5

p.S36T

c.107G>C

1 paper

NM_002834.5

p.S36I

c.107G>T

2 papers

NM_002834.5

p.N37T

c.110A>C

1 paper

NM_002834.5

p.S36R

c.106A>C

2 papers

NM_002834.5

p.S36G

c.106A>G

2 papers

NM_002834.5

p.N37S

c.110A>G