Varaico: Literature-Extracted Genetic Variants

PTPN11

3,412 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

SH2aa 6–81UCSCSH2 domain

SH2aa 112–197UCSCSH2 domain

Y_phosphataseaa 273–520UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 11

HGNC Previous Symbol

NS1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002834.5

p.G67A

c.200G>C

Surrounding Variants

1 paper

NM_002834.5

p.G67E

c.200G>A

2 papers

NM_002834.5

p.G67R

c.199G>A

2 papers

NM_002834.5

p.G67R

c.199G>C

2 papers

NM_002834.5

p.G68R

c.202G>A

1 paper

NM_002834.5

p.G68R

c.202G>C

1 paper

NM_002834.5

p.G68W

c.202G>T

1 paper

NM_002834.5

p.Y66F

c.197A>T

2 papers

NM_002834.5

p.G68V

c.203G>T

1 paper

NM_002834.5

p.G68G

c.204G>A

1 paper

NM_002834.5

p.G68_E69insFs

c.204_205ins7

1 paper

NM_002834.5

p.Y66D

c.196T>G

153 papers

NM_002834.5

p.E69K

c.205G>A