Varaico: Literature-Extracted Genetic Variants

Gene:PTPN2
Variant:p.W289*

PTPN2

141 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic ...

Pfam Domains

Y_phosphataseaa 42–274UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 2

HGNC Previous Symbol

PTPT

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_002828.4
p.W289*
c.867G>A
Surrounding Variants
2 papers
NM_002828.4
p.W289*
c.866G>A
3 papers
NM_002828.4
p.E291*
c.871G>T
1 paper
NM_002828.4
p.R288Q
c.863G>A
2 papers
NM_002828.4
p.R288*
c.862C>T
1 paper
NM_002828.4
p.K294Q
c.880A>C
2 papers
NM_002828.4
p.E295A
c.884A>C
1 paper
NM_002828.4
p.S298F
c.893C>T
1 paper
NM_002828.4
p.S304A
c.910T>G
1 paper
NM_002828.4
p.T331I
c.992C>T
1 paper
NM_002828.4
p.Q338E
c.1012C>G
1 paper
NM_002828.4
p.M341T
c.1022T>C
1 paper
NM_002828.4
p.Q286_K287Splc
c.858+4862T>C
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."