Varaico: Literature-Extracted Genetic Variants

Gene:PTPN2
Variant:p.Y126N

PTPN2

141 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic ...

Pfam Domains

Y_phosphataseaa 42–274UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 2

HGNC Previous Symbol

PTPT

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_002828.4
p.Y126N
c.376T>A
Surrounding Variants
1 paper
NM_002828.4
p.Q125*
c.373C>T
1 paper
NM_002828.4
p.T129P
c.385A>C
1 paper
NM_002828.4
p.M134L
c.400A>T
1 paper
NM_002828.4
p.M134L
c.400A>C
1 paper
NM_002828.4
p.F136L
c.406T>C
1 paper
NM_002828.4
p.F136L
c.408T>G
1 paper
NM_002828.4
p.F136L
c.408T>A
1 paper
NM_002828.4
p.S120L
c.359C>T
1 paper
NM_002828.4
p.A108fs
c.322_323fs
1 paper
NM_002828.4
p.W98*
c.294G>A
1 paper
NM_002828.4
p.W98*
c.293G>A
1 paper
NM_002828.4
p.H96Q
c.288T>A
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."