Varaico: Literature-Extracted Genetic Variants

PTPN21

110 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

FERM_Naa 27–90UCSCFERM N-terminal domain

FERM_Maa 106–222UCSCFERM central domain

FERM_Caa 226–312UCSCFERM C-terminal PH-like domain

Y_phosphataseaa 921–1166UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 21

HGNC Alias Symbols

PTPD1; PTPRL10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007039.4

p.H709Y

c.2125C>T

Surrounding Variants

1 paper

NM_007039.4

p.E712K

c.2134G>A

1 paper

NM_007039.4

p.S702delins

c.2105_2106delinsTC

1 paper

NM_007039.4

p.D716D

c.2148C>T

1 paper

NM_007039.4

p.H697Y

c.2089C>T

1 paper

NM_007039.4

p.Y695Y

c.2085C>T

1 paper

NM_007039.4

p.S723S

c.2169C>T

1 paper

NM_007039.4

p.A725T

c.2173G>A

1 paper

NM_007039.4

p.P728P

c.2184T>C

1 paper

NM_007039.4

p.P728delFs

c.2184delA

1 paper

NM_007039.4

p.P729fs

c.2185_2186fs

1 paper

NM_007039.4

p.S676R

c.2028C>G

1 paper

NM_007039.4

p.S676R

c.2028C>A