Varaico: Literature-Extracted Genetic Variants

PTPN21

110 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

FERM_Naa 27–90UCSCFERM N-terminal domain

FERM_Maa 106–222UCSCFERM central domain

FERM_Caa 226–312UCSCFERM C-terminal PH-like domain

Y_phosphataseaa 921–1166UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 21

HGNC Alias Symbols

PTPD1; PTPRL10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007039.4

p.Q382H

c.1146G>C

Surrounding Variants

1 paper

NM_007039.4

p.Q382H

c.1146G>T

2 papers

NM_007039.4

p.L385F

c.1153C>T

1 paper

NM_007039.4

p.L385P

c.1154T>C

1 paper

NM_007039.4

p.S377R

c.1131C>G

1 paper

NM_007039.4

p.S377R

c.1131C>A

1 paper

NM_007039.4

p.S377R

c.1129A>C

1 paper

NM_007039.4

p.T376S

c.1126A>T

1 paper

NM_007039.4

p.R390C

c.1168C>T

1 paper

NM_007039.4

p.R390H

c.1169G>A

1 paper

NM_007039.4

p.G369R

c.1105G>C

1 paper

NM_007039.4

p.G369R

c.1105G>A

1 paper

NM_007039.4

p.N405insFs

c.1214dupA