Varaico: Literature-Extracted Genetic Variants

PTPN21

110 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

FERM_Naa 27–90UCSCFERM N-terminal domain

FERM_Maa 106–222UCSCFERM central domain

FERM_Caa 226–312UCSCFERM C-terminal PH-like domain

Y_phosphataseaa 921–1166UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 21

HGNC Alias Symbols

PTPD1; PTPRL10

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_007039.4

p.I232V

c.694A>G

Surrounding Variants

1 paper

NM_007039.4

p.I232fs

c.694_695fs

1 paper

NM_007039.4

p.V243L

c.727G>T

1 paper

NM_007039.4

p.V243L

c.727G>C

1 paper

NM_007039.4

p.K246K

c.738G>A

1 paper

NM_007039.4

p.F254L

c.760T>C

1 paper

NM_007039.4

p.F254L

c.762T>G

1 paper

NM_007039.4

p.F254L

c.762T>A

1 paper

NM_007039.4

p.Q209L

c.626A>T

1 paper

NM_007039.4

p.E204fs

c.610_611fs

1 paper

NM_007039.4

p.A189S

c.565G>T

1 paper

NM_007039.4

p.F268L

c.802T>C

1 paper

NM_007039.4

p.F268L

c.804T>G