Varaico: Literature-Extracted Genetic Variants

PTPN22

621 papers

RefSeq Summary

This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with ...

Pfam Domains

Y_phosphataseaa 54–141UCSCProtein-tyrosine phosphatase

Y_phosphataseaa 54–288UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 22

HGNC Previous Symbol

PTPN8

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_015967.8

p.W620*

c.1859G>A

Surrounding Variants

40 papers

NM_015967.8

p.W620R

c.1858T>C

31 papers

NM_015967.8

p.W620R

c.1858T>A

2 papers

NM_015967.8

p.W620*

c.1860G>A

1 paper

NM_015967.8

p.P622L

c.1865C>T

1 paper

NM_015967.8

p.P622R

c.1865C>G

1 paper

NM_015967.8

p.I626I

c.1878T>C

1 paper

NM_015967.8

p.P614S

c.1840C>T

1 paper

NM_015967.8

p.E629K

c.1885G>A

1 paper

NM_015967.8

p.D611G

c.1832A>G

1 paper

NM_015967.8

p.D611N

c.1831G>A

1 paper

NM_015967.8

p.A606T

c.1816G>A

1 paper

NM_012411.6

p.A549A

c.1647A>G