Varaico: Literature-Extracted Genetic Variants

PTPN3

77 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

FERM_Naa 33–97UCSCFERM N-terminal domain

FERM_Maa 112–222UCSCFERM central domain

FERM_Caa 226–316UCSCFERM C-terminal PH-like domain

PDZaa 510–595UCSCPDZ domain

Y_phosphataseaa 670–900UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 3

HGNC Alias Symbol

PTPH1

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002829.4

p.D872E

c.2616T>G

Surrounding Variants

1 paper

NM_002829.4

p.D872E

c.2616T>A

1 paper

NM_002829.4

p.I873N

c.2618T>A

1 paper

NM_002829.4

p.R875*

c.2623C>T

1 paper

NM_002829.4

p.R864M

c.2591G>T

3 papers

NM_002829.4

p.C842S

c.2525G>C

3 papers

NM_002829.4

p.C842S

c.2524T>A

1 paper

NM_002829.4

p.P837S

c.2509C>T

1 paper

NM_002829.4

p.V833M

c.2497G>A

1 paper

NM_001145372.2

p.G481S

c.1441G>A

1 paper

NM_002829.4

p.H812L

c.2435A>T

2 papers

NM_002829.4

p.D811E

c.2433C>G

2 papers

NM_002829.4

p.D811E

c.2433C>A