Varaico: Literature-Extracted Genetic Variants

PTPN4

104 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

FERM_Naa 33–97UCSCFERM N-terminal domain

FERM_Maa 112–222UCSCFERM central domain

FERM_Caa 226–316UCSCFERM C-terminal PH-like domain

FAaa 323–366UCSCFERM adjacent (FA)

PDZaa 517–602UCSCPDZ domain

Y_phosphataseaa 679–910UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 4

HGNC Alias Symbol

PTPMEG

Papers

RefSeq ID

Protein change

DNA change

1–12 of 116 variants

5 papers

NM_002830.4

p.T924S

c.2770A>T

3 papers

NM_002830.4

p.L72S

c.215T>C

2 papers

NM_002830.4

p.R4C

c.10C>T

2 papers

NM_002830.4

p.R16R

c.48A>G

2 papers

NM_002830.4

p.Q52H

c.156A>T

2 papers

NM_002830.4

p.L64W

c.191T>G

2 papers

NM_002830.4

p.G239R

c.715G>A

2 papers

NM_002830.4

p.G239R

c.715G>C

2 papers

NM_002830.4

p.D580Y

c.1738G>T

2 papers

NM_002830.4

p.S689S

c.2067G>A

2 papers

NM_002830.4

p.I724T

c.2171T>C

2 papers

NM_002830.4

p.R808H

c.2423G>A