Varaico: Literature-Extracted Genetic Variants

PTPN4

104 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

FERM_Naa 33–97UCSCFERM N-terminal domain

FERM_Maa 112–222UCSCFERM central domain

FERM_Caa 226–316UCSCFERM C-terminal PH-like domain

FAaa 323–366UCSCFERM adjacent (FA)

PDZaa 517–602UCSCPDZ domain

Y_phosphataseaa 679–910UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 4

HGNC Alias Symbol

PTPMEG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002830.4

p.N230S

c.689A>G

Surrounding Variants

1 paper

NM_002830.4

p.N230_E231delFs

c.690_693del4

2 papers

NM_002830.4

p.G239R

c.715G>A

2 papers

NM_002830.4

p.G239R

c.715G>C