Varaico: Literature-Extracted Genetic Variants

PTPN4

104 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

FERM_Naa 33–97UCSCFERM N-terminal domain

FERM_Maa 112–222UCSCFERM central domain

FERM_Caa 226–316UCSCFERM C-terminal PH-like domain

FAaa 323–366UCSCFERM adjacent (FA)

PDZaa 517–602UCSCPDZ domain

Y_phosphataseaa 679–910UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 4

HGNC Alias Symbol

PTPMEG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002830.4

p.D580Y

c.1738G>T

Surrounding Variants

1 paper

NM_002830.4

p.G595R

c.1783G>A

1 paper

NM_002830.4

p.G595R

c.1783G>C

1 paper

NM_002830.4

p.M598I

c.1794G>A

1 paper

NM_002830.4

p.M598I

c.1794G>C

1 paper

NM_002830.4

p.M598I

c.1794G>T

1 paper

NM_002830.4

p.L600V

c.1798C>G

1 paper

NM_002830.4

p.R602*

c.1804C>T

1 paper

NM_002830.4

p.R602R

c.1806A>G

1 paper

NM_002830.4

p.E615Q

c.1843G>C

1 paper

NM_002830.4

p.V632E

c.1895T>A

1 paper

NM_002830.4

p.D636Y

c.1906G>T

1 paper

NM_002830.4

p.R640W

c.1918C>T