Varaico: Literature-Extracted Genetic Variants

PTPN4

104 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

FERM_Naa 33–97UCSCFERM N-terminal domain

FERM_Maa 112–222UCSCFERM central domain

FERM_Caa 226–316UCSCFERM C-terminal PH-like domain

FAaa 323–366UCSCFERM adjacent (FA)

PDZaa 517–602UCSCPDZ domain

Y_phosphataseaa 679–910UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 4

HGNC Alias Symbol

PTPMEG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002830.4

p.R758S

c.2272C>A

Surrounding Variants

1 paper

NM_002830.4

p.M748V

c.2242A>G

1 paper

NM_002830.4

p.Q739H

c.2217G>C

1 paper

NM_002830.4

p.Q739H

c.2217G>T

1 paper

NM_002830.4

p.Q739E

c.2215C>G

1 paper

NM_002830.4

p.D736N

c.2206G>A

1 paper

NM_002830.4

p.P731S

c.2191C>T

2 papers

NM_002830.4

p.I724T

c.2171T>C

1 paper

NM_002830.4

p.S775C

c.2324C>G

1 paper

NM_002830.4

p.Q780K

c.2338C>A

1 paper

NM_002830.4

p.M797R

c.2390T>G

1 paper

NM_002830.4

p.N708S

c.2123A>G

1 paper

NM_002830.4

p.K699*

c.2095A>T