Varaico: Literature-Extracted Genetic Variants

PTPN4

104 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

FERM_Naa 33–97UCSCFERM N-terminal domain

FERM_Maa 112–222UCSCFERM central domain

FERM_Caa 226–316UCSCFERM C-terminal PH-like domain

FAaa 323–366UCSCFERM adjacent (FA)

PDZaa 517–602UCSCPDZ domain

Y_phosphataseaa 679–910UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 4

HGNC Alias Symbol

PTPMEG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002830.4

p.D832N

c.2494G>A

Surrounding Variants

1 paper

NM_002830.4

p.L831I

c.2491C>A

1 paper

NM_002830.4

p.R838fs

c.2512_2513fs

2 papers

NM_002830.4

p.R838*

c.2512C>T

1 paper

NM_002830.4

p.R838Q

c.2513G>A

1 paper

NM_002830.4

p.C852insFs

c.2556dupC

1 paper

NM_002830.4

p.L810L

c.2430C>T

2 papers

NM_002830.4

p.R808H

c.2423G>A

1 paper

NM_002830.4

p.I872T

c.2615T>C

1 paper

NM_002830.4

p.E873D

c.2619A>C

1 paper

NM_002830.4

p.E873D

c.2619A>T

1 paper

NM_002830.4

p.M797R

c.2390T>G

1 paper

NM_002830.4

p.Q780K

c.2338C>A