Varaico: Literature-Extracted Genetic Variants

PTPN4

104 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

FERM_Naa 33–97UCSCFERM N-terminal domain

FERM_Maa 112–222UCSCFERM central domain

FERM_Caa 226–316UCSCFERM C-terminal PH-like domain

FAaa 323–366UCSCFERM adjacent (FA)

PDZaa 517–602UCSCPDZ domain

Y_phosphataseaa 679–910UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase non-receptor type 4

HGNC Alias Symbol

PTPMEG

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

5 papers

NM_002830.4

p.T924S

c.2770A>T

Surrounding Variants

1 paper

NM_002830.4

p.T924A

c.2770A>G

1 paper

NM_002830.4

p.E914K

c.2740G>A

1 paper

NM_002830.4

p.R902T

c.2705G>C

1 paper

NM_002830.4

p.E873D

c.2619A>C

1 paper

NM_002830.4

p.E873D

c.2619A>T

1 paper

NM_002830.4

p.I872T

c.2615T>C