protein tyrosine phosphatase non-receptor type 9

MEG2

Tyrosine-protein phosphatase non-receptor type 9

Protein-tyrosine phosphatase MEG2

PTPase MEG2

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis. [provided by RefSeq, Jul 2008].

Varaico: Literature-Extracted Genetic Variants

PTPN9

RefSeq Summary

Pfam Domains

Gene Aliases

HGNC Name

HGNC Alias Symbol