Varaico: Literature-Extracted Genetic Variants

PTPRB

204 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

fn3aa 111–198UCSCFibronectin type III domain

fn3aa 204–285UCSCFibronectin type III domain

fn3aa 288–371UCSCFibronectin type III domain

fn3aa 378–463UCSCFibronectin type III domain

fn3aa 468–551UCSCFibronectin type III domain

fn3aa 555–638UCSCFibronectin type III domain

Gene Aliases

HGNC Name

protein tyrosine phosphatase receptor type B

HGNC Previous Symbol

PTPB

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_001109754.4

p.V120A

c.359T>C

Surrounding Variants

1 paper

NM_001109754.4

p.V120I

c.358G>A

1 paper

NM_001109754.4

p.W130R

c.388T>C

1 paper

NM_001109754.4

p.W130R

c.388T>A

1 paper

NM_001109754.4

p.M131I

c.393G>T

1 paper

NM_001109754.4

p.M131I

c.393G>C

1 paper

NM_001109754.4

p.M131I

c.393G>A

1 paper

NM_001109754.4

p.L109V

c.325C>G

1 paper

NM_001109754.4

p.S108T

c.322T>A

2 papers

NM_001109754.4

p.E105K

c.313G>A

1 paper

NM_001109754.4

p.N136del1

c.406_407delGTT

1 paper

NM_001109754.4

p.E138K

c.412G>A

1 paper

NM_001109754.4

p.L102R

c.305T>G