Varaico: Literature-Extracted Genetic Variants

PTPRC

1,024 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

PTP_Naa 7–32UCSCProtein tyrosine phosphatase N terminal

CD45aa 237–295UCSCLeukocyte receptor CD45

fn3aa 483–568UCSCFibronectin type III domain

Y_phosphataseaa 677–911UCSCProtein-tyrosine phosphatase

Y_phosphataseaa 968–1227UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase receptor type C

HGNC Previous Symbol

CD45

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002838.5

p.L9_L10delFs

c.27_28delCT

Surrounding Variants

1 paper

NM_002838.5

p.K8Fs

c.24delinsGTFs

1 paper

NM_002838.5

p.K8E

c.22A>G

1 paper

NM_002838.5

p.L7_K8Fs

c.19_22delinsCTFs

1 paper

NM_002838.5

p.L10insFs

c.29_30insA

1 paper

NM_002838.5

p.A11T

c.31G>A

1 paper

NM_002838.5

p.A11V

c.32C>T

1 paper

NM_002838.5

p.F12I

c.34T>A

1 paper

NM_002838.5

p.F12fs

c.34_35fs

1 paper

NM_002838.5

p.Y4C

c.11A>G

1 paper

NM_002838.5

p.Y4F

c.11A>T

3 papers

NM_002838.5

p.G13D

c.38G>A

1 paper

NM_002838.5

p.M3K

c.8T>A