Varaico: Literature-Extracted Genetic Variants

PTPRC

1,024 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

PTP_Naa 7–32UCSCProtein tyrosine phosphatase N terminal

CD45aa 237–295UCSCLeukocyte receptor CD45

fn3aa 483–568UCSCFibronectin type III domain

Y_phosphataseaa 677–911UCSCProtein-tyrosine phosphatase

Y_phosphataseaa 968–1227UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase receptor type C

HGNC Previous Symbol

CD45

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002838.5

p.T55P

c.163A>C

Surrounding Variants

1 paper

NM_002838.5

p.H53Q

c.159C>A

1 paper

NM_002838.5

p.H53Q

c.159C>G

1 paper

NM_002838.5

p.A56A

c.168A>G

1 paper

NM_002838.5

p.F57I

c.169T>A

1 paper

NM_002838.5

p.F57L

c.171C>G

1 paper

NM_002838.5

p.T52I

c.155C>T

1 paper

NM_002838.5

p.T52A

c.154A>G

1 paper

NM_002838.5

p.S58A

c.172T>G

1 paper

NM_002838.5

p.P51S

c.151C>T

3 papers

NM_002838.5

p.P59P

c.177C>G

1 paper

NM_002838.5

p.L50*

c.149T>A

1 paper

NM_002838.5

p.L50_P51insFs

c.150_151ins4