Varaico: Literature-Extracted Genetic Variants

PTPRC

1,024 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

PTP_Naa 7–32UCSCProtein tyrosine phosphatase N terminal

CD45aa 237–295UCSCLeukocyte receptor CD45

fn3aa 483–568UCSCFibronectin type III domain

Y_phosphataseaa 677–911UCSCProtein-tyrosine phosphatase

Y_phosphataseaa 968–1227UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase receptor type C

HGNC Previous Symbol

CD45

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002838.5

p.T72T

c.216C>G

Surrounding Variants

1 paper

NM_002838.5

p.T72N

c.215C>A

2 papers

NM_002838.5

p.T73I

c.218C>T

1 paper

NM_002838.5

p.T74S

c.220A>T

1 paper

NM_002838.5

p.S77I

c.230G>T

1 paper

NM_002838.5

p.D79V

c.236A>T

1 paper

NM_002838.5

p.E66K

c.196G>A

1 paper

NM_002838.5

p.T81A

c.241A>G

1 paper

NM_002838.5

p.E64V

c.191A>T

1 paper

NM_002838.5

p.E64_F69delFs

c.192_205del14

1 paper

NM_002838.5

p.F63L

c.189T>A

1 paper

NM_002838.5

p.S82F

c.245C>T

1 paper

NM_002838.5

p.T62S

c.185C>G