Varaico: Literature-Extracted Genetic Variants

PTPRC

1,024 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

PTP_Naa 7–32UCSCProtein tyrosine phosphatase N terminal

CD45aa 237–295UCSCLeukocyte receptor CD45

fn3aa 483–568UCSCFibronectin type III domain

Y_phosphataseaa 677–911UCSCProtein-tyrosine phosphatase

Y_phosphataseaa 968–1227UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase receptor type C

HGNC Previous Symbol

CD45

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002838.5

p.P110L

c.329C>T

Surrounding Variants

1 paper

NM_002838.5

p.T111K

c.332C>A

1 paper

NM_002838.5

p.H108Q

c.324C>A

1 paper

NM_002838.5

p.H108Q

c.324C>G

1 paper

NM_002838.5

p.H112D

c.334C>G

1 paper

NM_002838.5

p.H108N

c.322C>A

1 paper

NM_002838.5

p.P107H

c.320C>A

1 paper

NM_002838.5

p.P107T

c.319C>A

1 paper

NM_002838.5

p.T106M

c.317C>T

1 paper

NM_002838.5

p.V104V

c.312A>G

1 paper

NM_002838.5

p.S103S

c.309A>C

1 paper

NM_002838.5

p.S102P

c.304T>C

1 paper

NM_002838.5

p.S102fs

c.304_305fs