Varaico: Literature-Extracted Genetic Variants

PTPRC

1,024 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

PTP_Naa 7–32UCSCProtein tyrosine phosphatase N terminal

CD45aa 237–295UCSCLeukocyte receptor CD45

fn3aa 483–568UCSCFibronectin type III domain

Y_phosphataseaa 677–911UCSCProtein-tyrosine phosphatase

Y_phosphataseaa 968–1227UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase receptor type C

HGNC Previous Symbol

CD45

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002838.5

p.W489*

c.1467G>A

Surrounding Variants

1 paper

NM_002838.5

p.W489*

c.1466G>A

1 paper

NM_002838.5

p.W489delFs

c.1466delG

1 paper

NM_002838.5

p.V488_W489delFs

c.1462_1465del4

1 paper

NM_002838.5

p.Q487R

c.1460A>G

1 paper

NM_002838.5

p.S486R

c.1458C>A

1 paper

NM_002838.5

p.S486R

c.1458C>G

1 paper

NM_002838.5

p.S486R

c.1456A>C

1 paper

NM_002838.5

p.P485T

c.1453C>A

1 paper

NM_002838.5

p.S494S

c.1482C>T

1 paper

NM_002838.5

p.S497*

c.1490C>A

1 paper

NM_002838.5

p.S497*

c.1490C>G

2 papers

NM_002838.5

p.D498E

c.1494T>A