Varaico: Literature-Extracted Genetic Variants

PTPRC

1,024 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

PTP_Naa 7–32UCSCProtein tyrosine phosphatase N terminal

CD45aa 237–295UCSCLeukocyte receptor CD45

fn3aa 483–568UCSCFibronectin type III domain

Y_phosphataseaa 677–911UCSCProtein-tyrosine phosphatase

Y_phosphataseaa 968–1227UCSCProtein-tyrosine phosphatase

Gene Aliases

HGNC Name

protein tyrosine phosphatase receptor type C

HGNC Previous Symbol

CD45

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

6 papers

NM_002838.5

p.Q1081Q

c.3243A>G

Surrounding Variants

1 paper

NM_002838.5

p.I1086T

c.3257T>C

1 paper

NM_002838.5

p.V1103I

c.3307G>A

1 paper

NM_002838.5

p.R1115*

c.3343C>T

1 paper

NM_002838.5

p.N1124delFs

c.3371delA

1 paper

NM_002838.5

p.N1124fs

c.3370_3371fs

2 papers

NM_002838.5

p.K1135T

c.3404A>C

1 paper

NM_002838.5

p.S1139F

c.3416C>T

1 paper

NM_002838.5

p.V1143V

c.3429C>A

1 paper

NM_002838.5

p.V1144I

c.3430G>A

1 paper

NM_002838.5

p.Q1150R

c.3449A>G

1 paper

NM_002838.5

p.E1155A

c.3464A>C

1 paper

NM_002838.5

p.I1167V

c.3499A>G