Varaico: Literature-Extracted Genetic Variants

PTPRF

257 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

I-setaa 33–124UCSCImmunoglobulin I-set domain

I-setaa 135–225UCSCImmunoglobulin I-set domain

I-setaa 232–315UCSCImmunoglobulin I-set domain

fn3aa 320–407UCSCFibronectin type III domain

fn3aa 415–506UCSCFibronectin type III domain

fn3aa 513–600UCSCFibronectin type III domain

Gene Aliases

HGNC Name

protein tyrosine phosphatase receptor type F

HGNC Previous Symbol

LAR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

4 papers

NM_002840.5

p.G342E

c.1025G>A

Surrounding Variants

1 paper

NM_002840.5

p.S344L

c.1031C>T

3 papers

NM_002840.5

p.S334R

c.1002T>A

3 papers

NM_002840.5

p.S334R

c.1002T>G

3 papers

NM_002840.5

p.S334R

c.1000A>C

1 paper

NM_002840.5

p.A356S

c.1066G>T

2 papers

NM_002840.5

p.A357V

c.1070C>T

1 paper

NM_002840.5

p.G358V

c.1073G>T

1 paper

NM_002840.5

p.K320M

c.959A>T

1 paper

NM_002840.5

p.R373C

c.1117C>T

1 paper

NM_002840.5

p.Y374H

c.1120T>C

2 papers

NM_002840.5

p.P381S

c.1141C>T

2 papers

NM_002840.5

p.P381L

c.1142C>T