Varaico: Literature-Extracted Genetic Variants

PTPRF

257 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

I-setaa 33–124UCSCImmunoglobulin I-set domain

I-setaa 135–225UCSCImmunoglobulin I-set domain

I-setaa 232–315UCSCImmunoglobulin I-set domain

fn3aa 320–407UCSCFibronectin type III domain

fn3aa 415–506UCSCFibronectin type III domain

fn3aa 513–600UCSCFibronectin type III domain

Gene Aliases

HGNC Name

protein tyrosine phosphatase receptor type F

HGNC Previous Symbol

LAR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002840.5

p.R448C

c.1342C>T

Surrounding Variants

1 paper

NM_002840.5

p.V449I

c.1345G>A

5 papers

NM_002840.5

p.Y450C

c.1349A>G

1 paper

NM_002840.5

p.R445Q

c.1334G>A

1 paper

NM_002840.5

p.R456C

c.1366C>T

1 paper

NM_002840.5

p.N460S

c.1379A>G

1 paper

NM_002840.5

p.A461G

c.1382C>G

1 paper

NM_002840.5

p.K464E

c.1390A>G

1 paper

NM_002840.5

p.K464K

c.1392G>A

2 papers

NM_002840.5

p.N466T

c.1397A>C

1 paper

NM_002840.5

p.A469A

c.1407G>A

1 paper

NM_002840.5

p.R419H

c.1256G>A

2 papers

NM_002840.5

p.R418C

c.1252C>T