Varaico: Literature-Extracted Genetic Variants

PTPRF

257 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

I-setaa 33–124UCSCImmunoglobulin I-set domain

I-setaa 135–225UCSCImmunoglobulin I-set domain

I-setaa 232–315UCSCImmunoglobulin I-set domain

fn3aa 320–407UCSCFibronectin type III domain

fn3aa 415–506UCSCFibronectin type III domain

fn3aa 513–600UCSCFibronectin type III domain

Gene Aliases

HGNC Name

protein tyrosine phosphatase receptor type F

HGNC Previous Symbol

LAR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002840.5

p.T605S

c.1813A>T

Surrounding Variants

1 paper

NM_002840.5

p.A602A

c.1806C>A

1 paper

NM_002840.5

p.R600H

c.1799G>A

1 paper

NM_002840.5

p.R600L

c.1799G>T

3 papers

NM_002840.5

p.V592I

c.1774G>A

1 paper

NM_002840.5

p.V590M

c.1768G>A

1 paper

NM_002840.5

p.T576_L577del1

c.1728_1730delACT

1 paper

NM_002840.5

p.T568_T576del0

c.1704_1727del24

1 paper

NM_002840.5

p.D562G

c.1685A>G

3 papers

NM_002840.5

p.D562N

c.1684G>A

1 paper

NM_002840.5

p.F561L

c.1683C>A

1 paper

NM_002840.5

p.F561L

c.1683C>G

1 paper

NM_002840.5

p.F561L

c.1681T>C