Varaico: Literature-Extracted Genetic Variants

PTPRF

257 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

I-setaa 33–124UCSCImmunoglobulin I-set domain

I-setaa 135–225UCSCImmunoglobulin I-set domain

I-setaa 232–315UCSCImmunoglobulin I-set domain

fn3aa 320–407UCSCFibronectin type III domain

fn3aa 415–506UCSCFibronectin type III domain

fn3aa 513–600UCSCFibronectin type III domain

Gene Aliases

HGNC Name

protein tyrosine phosphatase receptor type F

HGNC Previous Symbol

LAR

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

2 papers

NM_002840.5

p.A942V

c.2825C>T

Surrounding Variants

3 papers

NM_002840.5

p.R947C

c.2839C>T

1 paper

NM_002840.5

p.D937N

c.2809G>A

1 paper

NM_002840.5

p.T931S

c.2792C>G

1 paper

NM_002840.5

p.R956G

c.2866C>G

2 papers

NM_002840.5

p.R956L

c.2867G>T

1 paper

NM_002840.5

p.R897Q

c.2690G>A

1 paper

NM_002840.5

p.W991*

c.2973G>A

1 paper

NM_002840.5

p.R891R

c.2673G>A

1 paper

NM_002840.5

p.S996Y

c.2987C>A

1 paper

NM_002840.5

p.L882L

c.2646G>A

1 paper

NM_002840.5

p.L882insFs

c.2645_2646insA

1 paper

NM_002840.5

p.T878_V879del1

c.2634_2636delAGT