Varaico: Literature-Extracted Genetic Variants

PTPRS

194 papers

RefSeq Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell gro...

Pfam Domains

I-setaa 33–124UCSCImmunoglobulin I-set domain

Ig_3aa 135–220UCSCImmunoglobulin domain

Ig_3aa 244–315UCSCImmunoglobulin domain

fn3aa 333–420UCSCFibronectin type III domain

fn3aa 428–519UCSCFibronectin type III domain

Gene Aliases

HGNC Name

protein tyrosine phosphatase receptor type S

HGNC Alias Symbols

PTPsigma; PTP-sigma

Papers

RefSeq ID

Protein change

DNA change

Selected Variant

1 paper

NM_002850.4

p.L187delFs

c.559delG

Surrounding Variants

1 paper

NM_002850.4

p.Q186_R188del0

c.557_562del6

1 paper

NM_002850.4

p.L187_S189delFs

c.559_565del7

2 papers

NM_002850.4

p.R183C

c.547C>T

1 paper

NM_002850.4

p.G182*

c.544G>T

1 paper

NM_002850.4

p.D176Y

c.526G>T

1 paper

NM_002850.4

p.F169F

c.507C>T

1 paper

NM_002850.4

p.P162S

c.484C>T

1 paper

NM_002850.4

p.C156S

c.467G>C

1 paper

NM_002850.4

p.C156S

c.466T>A

1 paper

NM_002850.4

p.T153T

c.459C>T

1 paper

NM_002850.4

p.T153I

c.458C>T

1 paper

NM_002850.4

p.R148W

c.442C>T