Varaico: Literature-Extracted Genetic Variants

Gene:PTTG1
Variant:p.K9R

PTTG1

113 papers

RefSeq Summary

The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with ...

Pfam Domains

Securinaa 1–191UCSCSecurin sister-chromatid separation inhibitor

Gene Aliases

HGNC Name

PTTG1 regulator of sister chromatid separation, securin

HGNC Previous Symbol

TUTR1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004219.4
p.K9R
c.26A>G
Surrounding Variants
1 paper
NM_004219.4
p.K9M
c.26A>T
1 paper
NM_004219.4
p.L4L
c.12G>C
1 paper
NM_004219.4
p.T3N
c.8C>A
1 paper
NM_004219.4
p.A2V
c.5C>T
1 paper
NM_004219.4
p.M1insFs
c.3dupG
2 papers
NM_004219.4
p.A20A
c.60T>A
1 paper
NM_004219.4
p.K21*
c.61A>T
1 paper
NM_004219.4
p.L24Q
c.71T>A
1 paper
NM_004219.4
p.L26Q
c.77T>A
1 paper
NM_004219.4
p.L26P
c.77T>C
2 papers
NM_004219.4
p.G27G
c.81G>T
1 paper
NM_004219.4
p.S31A
c.91T>G
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