Varaico: Literature-Extracted Genetic Variants

Gene:PTTG1
Variant:p.I32N

PTTG1

113 papers

RefSeq Summary

The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase-promoting complex (APC) substrate that associates with ...

Pfam Domains

Securinaa 1–191UCSCSecurin sister-chromatid separation inhibitor

Gene Aliases

HGNC Name

PTTG1 regulator of sister chromatid separation, securin

HGNC Previous Symbol

TUTR1

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_004219.4
p.I32N
c.95T>A
Surrounding Variants
1 paper
NM_004219.4
p.K33R
c.98A>G
1 paper
NM_004219.4
p.T43A
c.127A>G
1 paper
NM_004219.4
p.T43K
c.128C>A
2 papers
NM_004219.4
p.K48R
c.143A>G
2 papers
NM_004219.4
p.T60A
c.178A>G
1 paper
NM_004219.4
p.T71A
c.211A>G
1 paper
NM_004219.4
p.E72D
c.216A>T
1 paper
NM_004219.4
p.T77A
c.229A>G
1 paper
NM_004219.4
p.L81F
c.241C>T
1 paper
NM_004219.4
p.K82R
c.245A>G
1 paper
NM_004219.4
p.K84N
c.252A>C
1 paper
NM_004219.4
p.K84N
c.252A>T
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