Varaico: Literature-Extracted Genetic Variants

Gene:PURA
Variant:p.K154fs

PURA

172 papers

RefSeq Summary

This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replic...

Pfam Domains

PurAaa 58–278UCSCPurA ssDNA and RNA-binding protein

Gene Aliases

HGNC Name

purine rich element binding protein A

HGNC Alias Symbols

PURALPHA; PUR1; PUR-ALPHA

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
2 papers
NM_005859.5
p.K154fs
c.460_461fs
Surrounding Variants
7 papers
NM_005859.5
p.R153P
c.458G>C
1 paper
NM_005859.5
p.R153fs
c.457_458fs
1 paper
NM_005859.5
p.Y155S
c.464A>C
1 paper
NM_005859.5
p.R153insFs
c.458_459dupGC
1 paper
NM_005859.5
p.Y156*
c.468C>A
2 papers
NM_005859.5
p.Y156*
c.468C>G
1 paper
NM_005859.5
p.M157L
c.469A>C
1 paper
NM_005859.5
p.M157L
c.469A>T
2 papers
NM_005859.5
p.E151*
c.451G>T
1 paper
NM_005859.5
p.E151_E161del11
c.451_482del33
6 papers
NM_005859.5
p.M157K
c.470T>A
4 papers
NM_005859.5
p.M157R
c.470T>G
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."