Varaico: Literature-Extracted Genetic Variants

Gene:RAG2
Variant:p.P421L

RAG2

397 papers

RefSeq Summary

This gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activ...

Pfam Domains

RAG2aa 51–389UCSCRecombination activating protein 2
RAG2_PHDaa 414–491UCSCRAG2 PHD domain

Gene Aliases

HGNC Name

recombination activating 2

HGNC Previous Name

recombination activating gene 2

Papers
RefSeq ID
Protein change
DNA change
Selected Variant
1 paper
NM_000536.4
p.P421L
c.1262C>T
Surrounding Variants
1 paper
NM_000536.4
p.P421H
c.1262C>A
1 paper
NM_000536.4
p.P421S
c.1261C>T
1 paper
NM_000536.4
p.P421T
c.1261C>A
2 papers
NM_000536.4
p.C419W
c.1257C>G
1 paper
NM_000536.4
p.C423S
c.1268G>C
4 papers
NM_000536.4
p.C423Y
c.1268G>A
1 paper
NM_000536.4
p.T418I
c.1253C>T
1 paper
NM_000536.4
p.D424V
c.1271A>T
1 paper
NM_000536.4
p.D426Y
c.1276G>T
1 paper
NM_000536.4
p.D426N
c.1276G>A
1 paper
NM_000536.4
p.W416*
c.1248G>A
15 papers
NM_000536.4
p.W416L
c.1247G>T
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."